Mounjaro vs Ozempic vs Wegovy: Which Weight Loss Injection is Right for You?

With so many weight loss injections now available, choosing the right one can feel overwhelming. At Fylde Private Medical, we're frequently asked to compare Mounjaro, Ozempic, and Wegovy. Here's an honest, clinically grounded breakdown.

The Key Difference: One Hormone vs Two

Ozempic and Wegovy both contain semaglutide, which targets a single hormone: GLP-1. Mounjaro contains tirzepatide, which targets both GLP-1 and GIP. This dual mechanism is why Mounjaro consistently achieves greater weight loss in clinical comparisons.

Mounjaro (Tirzepatide)

• Active ingredient: Tirzepatide

• Mechanism: Dual GLP-1 + GIP agonist

• Average weight loss: Up to 22.5% at highest dose

• Licensed for: Type 2 diabetes (weight loss is off-label but widely prescribed)

• At Fylde Private Medical: From £191/month

Wegovy (Semaglutide)

• Active ingredient: Semaglutide

• Mechanism: GLP-1 agonist only

• Average weight loss: Up to 15% at highest dose

• Licensed for: Weight management in adults

• At Fylde Private Medical: From £99/month

Ozempic (Semaglutide)

• Same active ingredient as Wegovy, but licensed for type 2 diabetes

• Frequently prescribed off-label for weight loss

• Lower dose ceiling than Wegovy for weight management

Which Should You Choose?

For most patients seeking maximum weight loss, Mounjaro is the stronger option based on clinical data. However, Wegovy may be preferable if you're earlier in your weight loss journey, working within a tighter budget, or if your GP identifies clinical reasons to prefer semaglutide.

This is exactly the kind of decision your GP at Fylde Private Medical will help you make — based on your health history, BMI, goals, and preferences — not based on what an algorithm suggests.